Help! Large table performance problem with MYSQL performance with ASP.NET

Large table performance problem with MYSQL performance with ASP.NET

I am doing some benchmarking of an application using MYSQL under
Windows and I confused about the results.

Environment
Emachine 6417 with amd3200+ 64 bit processor 3.3GB ram

mysql 4.1 with odbc 3.51 MYISAM
windows 2003 server std edition
date, account and invoice number are indexed
Database size 18 million rows

I am querying (selecting) columns of a date and an account

our tester program that opens a socket to the Mysql database and does a
select for the above n times
each time the date and the account is randomized to minimize hits on
records closeby.
This program will perform over 1000 queries per second.
At the end, the Mysql socket will be closed

When I enter a similar query manually a web interface, I get about 3
second response time.
This program opens/closes a socket for each query

Does anyone have any suggestions

Your assistance would be greatly appreciated

Also in production, this table will be accesse for both read and write
will I have problems. My testing showed that Innodb is much slower.

Murray
murray@jbmsystems.com
978-535-7676